TOXICITY IN RELATION TO STRUCTURE OF SUBSTITUTED 2H-1-BENZOPYRAN-2-ONES AGAINST ROOT-KNOT AND SEED-GALL NEMATODES

The toxicity of various hydroxy substituted 2H-1-benzopyran-2-ones (1a -c, 2 and 3), ester (1a-c, 5 and 6) and hydrazide (7a-c, 8 and 9) deri vatives of 2H-1-benzopyranyloxyacetic acids and 2H-1-benzopyranyloxyac etylpiperidines (10a-c, 11 and 12) and corresponding morpholines (13a- c, 14 and 15) was determined against second stage juveniles of root-kn ot nematode (Meloidogyne javanica) and seed-pall nematode (Anguina tri tici). Several of the compounds showed appreciable toxicity against bo th the tested nematodes. The activity results are discussed in relatio n to structure of the compounds. In general, the free phenolic compoun d and derived esters exhibited better toxicity.