Heart rates (HR) were measured before (control HR) and after (ischemic
HR) balloon inflation during percutaneous transluminal coronary angio
plasty in 96 patients with effort angina pectoris. The delta HR, defin
ed as (ischemic HR-control HR), in the right coronary artery occlusion
was significantly smaller than that in the left anterior descending a
rtery or left circumflex artery occlusion. Among right coronary artery
occlusions the delta HR in segment 1 occlusion was significantly smal
ler than that in segment 2 or segment 3 occlusion. It is suggested tha
t the ischemia of the right ventricle plays an important role in produ
cing a reflex bradycardic response in humans.