DIAGNOSTIC-VALUE OF DETECTING JC VIRUS-DNA IN CEREBROSPINAL-FLUID OF PATIENTS WITH PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Authors
FONG IW BRITTON CB LUINSTRA KE TOMA E MAHONY JB
Citation
Iw. Fong et al., DIAGNOSTIC-VALUE OF DETECTING JC VIRUS-DNA IN CEREBROSPINAL-FLUID OF PATIENTS WITH PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY, Journal of clinical microbiology, 33(2), 1995, pp. 484-486
Citations number
17
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
33
Issue
2
Year of publication
1995
Pages
484 - 486
Database
ISI
SICI code
0095-1137(1995)33:2<484:DODJVI>2.0.ZU;2-G
Abstract
JC virus DNA was detected by PCR in the cerebrospinal fluid of 17 of 2 3 (73.9%) patients with confirmed cases of progressive multifocal leuk oencephalopathy and 2 of 48 (4.2%) controls without progressive multif ocal leukoencephalopathy. The sensitivity and specificity of this PCR were 74 and 95.8%, respectively, while the positive and negative predi ctive values were 89.5 and 88.5%, respectively.