A FORMAL SYNTHESIS OF NAUCLEFINE

Authors
VOHRA R MACLEAN DB
Citation
R. Vohra et Db. Maclean, A FORMAL SYNTHESIS OF NAUCLEFINE, Heterocycles, 39(2), 1994, pp. 445-448
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
39
Issue
2
Year of publication
1994
Pages
445 - 448
Database
ISI
SICI code
0385-5414(1994)39:2<445:AFSON>2.0.ZU;2-0
Abstract
The amidine (2) has been prepared in three steps from the enolate of ( 3-cyanopyridin-4-yl)acetaldehyde and tryptamine hydrochloride by way o f the enamine (5) and the 1,2,3,4-tetrahydro-beta-carboline (6). The c onversion of 2 into nauclefine has been previously reported.