G. Dornyei et al., INVESTIGATIONS ON THE CHEMISTRY OF BERBANES .14. A NOVEL STEREOSELECTIVE APPROACH TO BIOLOGICALLY-ACTIVE ALLO-BERBANE DERIVATIVES, Heterocycles, 39(2), 1994, pp. 449-456
Stereoselective total synthesis of alpha(2) adrenoceptor agents (1) an
d (2) with allo-berbane skeleton has been performed via Knoevenagel-ty
pe condensation of ketones (3).