The syntheses of tris- and tetrakis(tropocoronand)s, a kind of macrocy
cles derived three or four aminotropone imine moieties bridged by thre
e or four short methylene linker chains are described. These tropocoro
nands were prepared by the reaction of bis(2-methoxytropone imine)salt
s with alpha,omega-alkanediamine using a template or with tropopodand
derived from benzo[b]cyclohepta[e][1,4]oxazine with N-acetyl-1,2-ethan
ediamine by an intermolecular heterocycle exchange reaction.