NEW TETRACYCLIC DERIVATIVES OF IMIDAZO[1,5-A][1,4]BENZODIAZEPINES ANDOF IMIDAZO[1,5-A]THIENO[3,2-F][1,4]DIAZEPINES

Authors
GERECKE M KYBURZ E BORER R GASSNER W
Citation
M. Gerecke et al., NEW TETRACYCLIC DERIVATIVES OF IMIDAZO[1,5-A][1,4]BENZODIAZEPINES ANDOF IMIDAZO[1,5-A]THIENO[3,2-F][1,4]DIAZEPINES, Heterocycles, 39(2), 1994, pp. 693-721
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
39
Issue
2
Year of publication
1994
Pages
693 - 721
Database
ISI
SICI code
0385-5414(1994)39:2<693:NTDOIA>2.0.ZU;2-T
Abstract
The synthesis of new tetracyclic 1,4-diazepine derivatives is describe d. In these compounds, an additional five-membered heterocycle is fuse d on the known tricyclic ring systems imidazo[1,5-a][1,4]benzodiazepin e and imidazo[1,5-a]thieno[3,2-f][1,4]diazepine. Many of these new com pounds display a very high affinity to the benzodiazepine receptor in mammals.