CONCURRENT LYMPHANGIOMA, IMMUNE-MEDIATED THROMBOCYTOPENIA, AND VON WILLEBRANDS DISEASE IN A DOG

Citation
Jp. Woods et al., CONCURRENT LYMPHANGIOMA, IMMUNE-MEDIATED THROMBOCYTOPENIA, AND VON WILLEBRANDS DISEASE IN A DOG, The Journal of the American Animal Hospital Association, 31(1), 1995, pp. 70-76
Citations number
28
Categorie Soggetti
Veterinary Sciences
ISSN journal
05872871
Volume
31
Issue
1
Year of publication
1995
Pages
70 - 76
Database
ISI
SICI code
0587-2871(1995)31:1<70:CLITAV>2.0.ZU;2-4
Abstract
Lymphangioma, immune-mediated thrombocytopenia (IMT), and von Willebra nd's disease (vWD) were diagnosed by histology, hematology, and a coag ulation profile in a 14-month-old, female dachshund. Clinical and labo ratory findings included ecchymotic inguinolabial swelling, thrombocyt openia, positive platelet factor-3 assay, prolonged buccal mucosal ble eding time, and subnormal von Willebrand factor antigen concentration and factor VIII activity. The IMT resolved with immunosuppressive gluc ocorticoid therapy Histologic examination identified lymphangioma whic h was too extensive for surgical excision. The history and the clinica l and laboratory findings were consistent with congenital vWD, althoug h acquired vWD secondary to lymphangioma could not be ruled out.