Independent lung ventilation using two ventilators has been attempted
in the treatment of acute respiratory failure due to unilateral lung d
isease. However, this method has been found to be cumbersome and diffi
cult to use. We reasoned that a bifurcated endotracheal tube with a va
riable resistance valve may enable us to change the inspiratory airway
pressures and, hence, the inspired tidal volume to one lung using a s
ingle ventilator. We tested this hypothesis in eight anesthetized shee
p and created a bronchopleural fistula in one lung as a model of unila
teral lung disease. A bifurcated endotracheal tube was placed to separ
ate the ventilation to each lung and, through a ''Y'' connector, both
right and left lungs were ventilated simultaneously with a single vent
ilator. A variable resistance valve was placed between the ''Y'' conne
ctor and the tube ventilating the experimental lung with bronchopleura
l fistula. With a ventilator-generated peak inspiratory pressure of 31
+/-2 cm H2O, the airway pressure distal to the valve was randomly chan
ged from 31 cm H2O to 23+/-2, 15+/-1, 8+/-1, and 0 cm H2O. This result
ed in progressive diversion of tidal volume from the experimental lung
to the control lung and an increase in exhaled tidal volume due to a
decrease in air leak from the bronchopleural fistula. These data sugge
st that a variable resistance valve may be used for independent lung v
entilation using a single ventilator.