Nn. Solovykh et Ag. Korotkov, ANTIEPILEPTIC EFFECTS OF LAMIKTAL IN YOUN G-CHILDREN AND ADOLESCENTS, Zurnal nevropatologii i psihiatrii im. S.S. Korsakova, 94(4), 1994, pp. 9-12
Antiepileptic effects of lamiktal (lamotrigine) produced in Great Brit
ain (Wellcome) was tried in 7 children aged 3 - 14 and 3 adults aged 1
8 - 30. Of them 6 patients and 4 patients suffered from temporal polim
orphic fits and general paroxysms, respectively. Upon 3-month follow-u
p it was found that the fits discontinued in 4 patients, frequency of
the paroxysms reduced or they became abortive in 6 cases. EEG changes
were insignificant. No side effects occurred. Lamiktal is recommended
in polymorphic seizures in children and adults, in failure of other an
ticonvulsants in patients frequently affected with epileptic paroxysms
.