CIRCULATING ANTIBODIES TO MEMBRANE-COMPON ENTS OF ADIPOSE-TISSUE IN BREAST-CANCER PATIENTS AND HEALTHY WOMEN - INTERRELATIONSHIPS WITH EXCESSIVE BODY-MASS AND HYPERLIPIDEMIA

Authors
BERSTEIN LM ZAKHAROVA GA KOVALENKO IG KRYUKOVA OG SHEMEROVSKAYA TG
Citation
Lm. Berstein et al., CIRCULATING ANTIBODIES TO MEMBRANE-COMPON ENTS OF ADIPOSE-TISSUE IN BREAST-CANCER PATIENTS AND HEALTHY WOMEN - INTERRELATIONSHIPS WITH EXCESSIVE BODY-MASS AND HYPERLIPIDEMIA, Eksperimental'naa onkologia, 16(2-3), 1994, pp. 191-194
Citations number
14
Categorie Soggetti
Oncology
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
16
Issue
2-3
Year of publication
1994
Pages
191 - 194
Database
ISI
SICI code
0204-3564(1994)16:2-3<191:CATMEO>2.0.ZU;2-W
Abstract
When observing healthy women and breast cancer patients in some of the m in reaction of passive hemagglutinization there were found blood ant ibodies to membrane components of human adipose tissue. The frequency of autoantibodies detection to ''pure'' antigen (got by means of colla genase and ultracentrifugation in percoll gradient) in breast cancer p atients 1.7-fold exceeded that one in healthy women. The mentioned ant ibodies were more frequently found in patients with central (''upper'' ) type of fat deposition, and their higher titer was observed in patie nts and healthy women with hyperlipidemia. Tumor factors probably infl uence the development (progression) of autoimmune process in adipose t issue.