REACTION OF 2-DEOXYGUANOSINE WITH GLUCOSE

Authors
Citation
S. Ochs et T. Severin, REACTION OF 2-DEOXYGUANOSINE WITH GLUCOSE, Carbohydrate research, 266(1), 1995, pp. 87-94
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00086215
Volume
266
Issue
1
Year of publication
1995
Pages
87 - 94
Database
ISI
SICI code
0008-6215(1995)266:1<87:RO2WG>2.0.ZU;2-Y
Abstract
Glucose reacts with 2'-deoxyguanosine under physiological conditions t o give the diastereomeric purine substituted trihydroxy-alpha-amino he xanoic acids 4 as main products. Hydrolysis of 4 leads to the guanine derivatives 6 which have been synthesized by an independent route.