MOLECULAR CHARACTERIZATION OF THE SALMONELLA-TYPHI STPA PROTEIN THAT IS RELATED TO BOTH YERSINIA YOPE CYTOTOXIN AND YOPH TYROSINE PHOSPHATASE

Authors
ARRICAU N HERMANT D WAXIN H POPOFF MY
Citation
N. Arricau et al., MOLECULAR CHARACTERIZATION OF THE SALMONELLA-TYPHI STPA PROTEIN THAT IS RELATED TO BOTH YERSINIA YOPE CYTOTOXIN AND YOPH TYROSINE PHOSPHATASE, Research in microbiology, 148(1), 1997, pp. 21-26
Citations number
27
Categorie Soggetti
Microbiology
Journal title
Research in microbiology → ACNP
ISSN journal
09232508
Volume
148
Issue
1
Year of publication
1997
Pages
21 - 26
Database
ISI
SICI code
0923-2508(1997)148:1<21:MCOTSS>2.0.ZU;2-V
Abstract
Analysis of the nucleotide sequence of a 4-kb DNA fragment located bet ween the sip and iag loci on Salmonella typhi chromosome revealed thre e open reading frames, termed sipF, ctpA and stpA, The 82-amino-acid ( aa) sipF product showed extensive similarity to the lacP protein from S. typhimurium. The StpA protein (535 aa) exhibited significant simila rity to both Yersinia enterocolitica YopE cytotoxin and YopH tyrosine phosphatase. The CtpA polypeptide (130 aa) might be the molecular chap erone of the StpA protein.