IMMUNODIAGNOSTIC POTENTIAL OF A FILARIAL PROTEASE

Authors
BAL M DAS MK
Citation
M. Bal et Mk. Das, IMMUNODIAGNOSTIC POTENTIAL OF A FILARIAL PROTEASE, Current Science, 67(12), 1994, pp. 1018-1020
Citations number
12
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Current Science → ACNP
ISSN journal
00113891
Volume
67
Issue
12
Year of publication
1994
Pages
1018 - 1020
Database
ISI
SICI code
0011-3891(1994)67:12<1018:IPOAFP>2.0.ZU;2-F
Abstract
An antigenic fraction has been isolated from adult worms of cattle fil arial parasite Setaria digitata. The fraction exhibited high protease activity against azocoll with optimum pH at 7.0. Elevated levels of an tibodies to the protease were observed in asymptomatic microfilaraemic individuals compared to the normal people of endemic regions. Such di stinction was however not observed with the whole antigenic extracts o f adult worms. The potential of the protease as immunodiagnostic antig en is indicated.