CURRENT PROBLEMS IN PSYCHOPHARMACOLOGY

The basic principle of psychopharmacology - is its impact on the psych opathological syndrome, having in view its specificity, expressivity o f negative disturbances, nozological entity. One of the approaches to the selection of adequate psychopharmacotherapy may be the concept of comorbidity of disturbances, determining the structure of the syndrome and perspectives of its impact. With this in view, the structure of s ome syndromes may be considered not as a complex of closely interrelat ed disturbances, but as states stemming from relatively independent pa thological disturbances, connected by probable relations. The problem of differentiated psychopharmacotherapy in line with the phenomenon of comorbidity at the level of symptom-syndrome, psychopathological pers onality disturbances (including negative ones), may have a practical a s well as a theoretical significance. An analysis of comorbid connecti ons determines as well the selection of preventive drugs in the prophy laxis of relapses of psychoses. An eventual study of all sides of this problem has its goal to define the spectre of action of the already k nown drugs and new psychopharmacological preparations, a deeper unders tanding of psychopathology and the clinical state being under the impa ct of psycopharmacological therapy, a transition from an extensive und erstanding of a wide range of questions of psycopharmacology to an int ensive study of separate facets of the problem, which seems to be most perspective.