CLINICAL USE OF METHYLPREDNISOLONE SODIUM SUCCINATE - A REVIEW

Methylprednisolone sodium succinate is an injectable form of the corti costeroid methylprednisolone. Because it is extremely soluble in water , intravenous methylprednisolone can be administered in a small volume of diluent. This characteristic is particularly beneficial when high blood levels of methylprednisolone must be achieved rapidly. Methylpre dnisolone sodium succinate therapy is useful in the management of many conditions seen by primary care and emergency department physicians, including allergic states, collagen disease, dermatologic conditions, cerebral and spinal edema, gastrointestinal disorders, neoplastic dise ase, nervous system disorders, rejection of transplanted organs, respi ratory tract disease, and acute spinal cord injuries. Although intrave nous methylprednisolone has widespread therapeutic uses, long-term the rapy is associated with potentially serious adverse effects. Therefore , whenever methylprednisolone sodium succinate is prescribed, the clin ician must individualize the dosage to ensure that the patient receive s the lowest effective dose.