FLUORESCENCE PROPERTIES OF OXIDIZED HUMAN PLASMA LOW-DENSITY LIPOPROTEINS

Appearance of fluorescence emission between 380-550 nm (lambda exc 350 -400 nm) in freshly prepared low-density lipoprotein from asymptomatic normolipemic human plasma revealed the presence of in vivo oxidative modification of its protein moiety. Low-density lipoprotein elicited s even fluorophores in three dimensional fluorescence spectrogram. Assig nment of fluorescent chemical structures originating from oxidative mo dification of the protein moiety of low-density lipoprotein has been m ade with the help of second derivative fluorescence spectroscopy.