Objective: To test the hypothesis that the erosion of family structure
, epidemic substance abuse, and increased low birth weight (LBW) rates
are interrelated. Methods: In this cohort study, we analyzed informat
ion coded prospectively in a computerized perinatal data base. Separat
ed, divorced, and widowed mothers were grouped as broken marriages. Th
e setting was a predominantly urban, indigent population in a tertiary
care hospital. The analysis included singleton pregnancies of 14,896
women receiving prenatal and intrapartum care at our hospital from 198
6-1991. The main outcome measures included LBW, prematurity, small for
gestational age, neonatal mortality, and neonatal intensive care unit
admissions. Results: Married mothers fared better than single mothers
, but risks for adverse perinatal outcomes for women with broken marri
ages were consistently as high or higher than for single mothers. The
rate of LBW infants was 43% higher in the broken marriage group than i
n the married group. The increased frequency of LBW among infants born
into broken marriages was attributable mainly to reduced growth rathe
r than to prematurity and was associated with substance abuse. Conclus
ion: Our findings indicate that mothers from broken marriages are at r
elatively higher risk for LBW infants than married mothers (odds ratio
1.5). Broken marriage warrants emphasis as an important perinatal ris
k factor.