Objective To evaluate the impact of radical prostatectomy (RP) upon qu
ality of life (QOL) in patients with prostate cancer. Patients and met
hods Seventy-nine patients with prostate cancer were recruited to eval
uate the impact of RP upon QOL. The patients comprised two groups: the
first group (n = 51) was evaluated 12 months or longer after RP; and
the second group (n = 28) was evaluated 1 month prior to RP. All patie
nts completed two previously reported QOL measures: the Functional Liv
ing Index Cancer (FLIC) and Profile of Mood States (POMS), and a serie
s of questions which evaluated bladder, bowel and sexual function. Res
ults Comparison of patients before RP with those after RP at 12 month
follow-up revealed significant (P<0.05) deterioration in sexual functi
on, continence and hardship scores following RP while tension scores i
mproved significantly. Although 10 other subscale parameters were anal
ysed, no other differences were observed. Of the 51 post-RP patients,
46 (90%) stated that given a choice they would have their surgery agai
n. Conclusion The results reported show that RP has minimal overall im
pact upon patient QOL. Although minimal voiding and bowel dysfunction
was reported, many patients were dissatisfied with post-operative sexu
al function.