The relationship between basic research with nonhumans and applied beh
avior analysis is illustrated by our work on activity anorexia. When r
ats are fed one meal a day and allowed to run on an activity wheel, th
ey run excessively, stop eating, and die of starvation. Convergent evi
dence, from several different research areas, indicates that the behav
ior of these animals and humans who self-starve is functionally simila
r. A biobehavioral theory of activity anorexia is presented that detai
ls the cultural contingencies, behavioral processes, and physiology of
anorexia. Diagnostic criteria and a three-stage treatment program for
activity-based anorexia are outlined. The animal model permits basic
research on anorexia that for practical and ethical reasons cannot be
conducted with humans. Thus, basic research can have applied importanc
e.