Diabetic transplant recipients are at a high risk for foot pathology l
eading to amputation. This retrospective study from 1/85 to 2/92 exami
nes the risk of foot complications in a population (n=340) of diabetic
renal and combined renal/pancreas transplant recipients. All groups s
uffered high lower extremity amputation and foot fracture rates. Patie
nts with better circulation and protective sensation intact fared bett
er Smoking had a profoundly negative effect on the amputation rate as
did an amputation prior to the transplant. Patients with pretransplant
dialysis were at a higher risk for post-transplant amputation. Concom
itant pancreas transplant did not in general significantly affect the
risk of amputation or fracture. Females had almost twice the fracture
rate of males.