A NOVEL-APPROACH TOWARDS THE SYNTHESIS OF PYROPHOSPHATE ANALOGS OF FARNESYL PYROPHOSPHATE

Authors
VALENTIJN ARPM VANDENBERG O VANDERMAREL GA COHEN LH VANBOOM JH
Citation
Arpm. Valentijn et al., A NOVEL-APPROACH TOWARDS THE SYNTHESIS OF PYROPHOSPHATE ANALOGS OF FARNESYL PYROPHOSPHATE, Recueil des travaux chimiques des Pays-Bas, 113(12), 1994, pp. 563-566
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Recueil des travaux chimiques des Pays-Bas → ACNP
ISSN journal
01650513
Volume
113
Issue
12
Year of publication
1994
Pages
563 - 566
Database
ISI
SICI code
0165-0513(1994)113:12<563:ANTTSO>2.0.ZU;2-A
Abstract
The synthesis of two new analogues (i.e. 3 and 4) of farnesyl pyrophos phate (FPP) containing a phosphonophosphate and a phosphonophosphonate moiety was accomplished via the phosphonomorpholidate. The latter was easily obtained by treatment of a phosphonic chloride with morpholine .