Ls. Berman et al., A NEW PEDIATRIC RESPIRATORY MONITOR THAT ACCURATELY MEASURES IMPOSED WORK OF BREATHING - A VALIDATION-STUDY, Journal of clinical monitoring, 11(1), 1995, pp. 14-17
Objective. A new, microproccssor-controlled respiratory monitor (model
CP-100 Pediatric, Bicore Monitoring Systems, Irvine, CA) that measure
s imposed work of breathing and a variety of respiratory parameters fo
r pediatric patients receiving ventilatory support has recently been d
eveloped. To validate its accuracy, measurements obtained using this m
onitor were compared with those obtained using conventional laboratory
equipment. Methods. An in vitro lung model was used to simulate spont
aneously breathing pediatric patients ranging from infancy to 10 years
of age. Tidal volume, respiratory rate, and peak inspiratory flow rat
es were simulated in a stepwise manner. Values for imposed work, tidal
volume, peak inspiratory flow rate, and change in airway pressure for
both methods were compared using regression analysis. Results. The co
efficients of determination (r(2)) describing the relationships of bot
h methods of measuring imposed work, tidal volume, peak inspiratory fl
ow rate, and the change in airway pressure ranged from 0.99 to 1.00, a
nd were highly significant (p < 0.001). For all measurements, bias was
minimal and precision was calculated. Conclusions. Our data reveal th
at this pediatric respiratory monitor accurately measures imposed work
of breathing, as well as tidal volume, flow rate, and airway pressure
. Imposed work of breathing measurements obtained from the monitor may
be used to adjust pressure support ventilation, so that the imposed w
ork of the breathing apparatus is reduced to zero and the patient's to
tal work of breathing is thus decreased.