A case of osseous fluorosis in a 61-year-old man hospitalized for a si
x-month history of slowly progressive cervical spinal cord compression
is reported. Roentgenograms of the cervical, thoracic, and lumbar spi
ne disclosed diffuse vertebral sclerosis, calcifications of the interv
ertebral ligaments and disks, and posterior spinal osteophytosis. Calc
ification of the tibiofibular membrane suggestive of fluorosis was see
n on roentgenograms of the legs. Investigations found no evidence of r
enal disease, parathyroid gland dysfunction, or malignant disease. Uri
nary fluoride excretion was elevated (3.04 mg/24 h). Cervical computed
tomography disclosed severe spinal cord compression due to posterior
osteophytes. Decompressive surgery was followed by marked improvement.
Osteophytosis, which mainly affects the cervical spine, is among the
mechanisms responsible for the cervical myelopathy associated with flu
orosis.