The Glasgow Register of Congenital Anomalies reports the highest birth
prevalence of congenital anomalies af all 18 participating centres in
the EUROCAT project for the years 1980 to 1988. A high prevalence is
found in most defect categories, with Glasgow in the top three places
in the EUROCAT ''league'' in 7 of the IO categories studied. While the
high rate could reflect a high level of ascertainment, we have conclu
ded that there is enough reason to be seriously concerned that the hig
h Glasgow rate is a reflection of risk rather than methodology.