Introduction. There are many skin manifestations of Crohn's disease in
cluding specific lesions occurring late after digestive signs. These m
anifestations are also termed metastatic and are rarely located on the
vulva. Case report : We observed a metastatic localization in the vul
va of Crohn's disease in a 34-year-old woman with predominantly rectos
igmoid disease. The right labia major was greatly enlarged with oedema
involving the inguinal cural area. Pustulization and erosive lesions
were seen. The course of these lesions was independent of the colonic
disease and responded temporarily only to a triple drug combination of
metronidazol, prednisolone and minocyclin. Conclusion. This case emph
asizes the frequency of colonic or rectal manifestations associated wi
th vulval involvement in Crohn's disease. The metastatic lesions follo
w a course independent of the digestive disease raising therapeutic pr
oblems in this localization.