We present true patients with bilateral lesions of the superior tempor
al cortex who manifested a number of functional dissociations in the a
uditory domain. The perception of speech and environmental sounds were
preserved; yet, the perception of times, prosody and voice was impair
ed. As the processing of melodic but not rhythmic variations in musica
l sequences was selectively disturbed, the deficit cannot be attribute
d to a general impairment in auditory memory or sequential processing.
These findings suggest that melody processing is not mediated by a ge
neral-purpose auditory architecture bur by specialized cortical subsys
tems residing within the lesioned areas. Current taxonomies of auditor
y agnosia and models of normal music cognition are evaluated in light
of the functional dissociations manifested by these patients.