ASSIGNMENT OF A HUMAN AUTOIMMUNE ANTIGEN, P80-COILIN GENE TO CHROMOSOME 17Q21-Q23 AND OF ITS POSSIBLE PSEUDOGENE TO CHROMOSOME-14

Authors
KUSUDA J TANUMA R GOTOH E TOYODA A HASHIMOTO K
Citation
J. Kusuda et al., ASSIGNMENT OF A HUMAN AUTOIMMUNE ANTIGEN, P80-COILIN GENE TO CHROMOSOME 17Q21-Q23 AND OF ITS POSSIBLE PSEUDOGENE TO CHROMOSOME-14, Human genetics, 95(2), 1995, pp. 233-234
Citations number
5
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
95
Issue
2
Year of publication
1995
Pages
233 - 234
Database
ISI
SICI code
0340-6717(1995)95:2<233:AOAHAA>2.0.ZU;2-U
Abstract
In order to determine the chromosomal locations of an autoimmune antig en, the coilin gene and its pseudogene, we amplified the segments of t he two genes by the polymerase chain reaction (PCR) and screened a pan el of somatic cell hybrids for the presence of the gene products. The results indicate that the human coilin gene and its pseudogene can be assigned to chromosome 17 and chromosome 14, respectively. Further ana lysis of cell hybrids bearing chromosome 17 with various deletions loc alized the coilin gene to the region q21-q23.