A total of 15 chronic renal failure patients on hemodialysis therapy u
nderwent some kind of cardiovascular surgery between August 1984 and M
arch 1993. Ten had a valve abnormality, and the remaining five had cor
onary artery disease. All of them were hemodialyzed the day before sur
gery and 24-48 h after the operation. Eleven recovered well after surg
ery, four died of septic shock: two of these were in septic shock prio
r to surgery; one was in acute congestive heart failure, and one was o
perated during an acute myocardial infarction. All operative deaths oc
curred in the patients who underwent non-elective surgery or were preo
peratively in New Heart Association (NYHA) class IV. The factors havin
g an impact on morbidity and mortality seem to be more related to the
previous clinical situation and to the urgency of the operation than t
o the status of chronic renal failure. An early and adequate assessmen
t of the candidates, when possible avoiding emergency surgery and acut
e left ventricular dysfunction, as well as careful management during c
ardiopulmonary bypass procedures (CPB) and the immediate post-surgical
period will certainly improve the result of cardiac surgery in these
patients, making it similar to those who are not in chronic renal fail
ure.