NEW STRATEGY FOR THE SYNTHESIS OF 4 INDIVIDUAL ISOMERS OF BETA-METHYLPHENYLALANINE

Authors
LUNG FD LI GG LOU BS HRUBY VJ
Citation
Fd. Lung et al., NEW STRATEGY FOR THE SYNTHESIS OF 4 INDIVIDUAL ISOMERS OF BETA-METHYLPHENYLALANINE, Synthetic communications, 25(1), 1995, pp. 57-61
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
1
Year of publication
1995
Pages
57 - 61
Database
ISI
SICI code
0039-7911(1995)25:1<57:NSFTSO>2.0.ZU;2-J
Abstract
The application of an allylic strain effect in boron enolates and asym metric Michael-like addition/electrophilic bromination reactions is re ported for the asymmetric synthesis of the individual isomers of unusu al constrained amino acids. For beta-substituted alpha-amino acids, al l of the final optically pure products were identical to authentic sam ples, which provided further and unequivocal evidence to confirm the a ssignments of stereochemical control of the new methods in this report .