IMMUNOFLUORESCENCE STUDY OF IMMUNE-COMPLEXES IN POLYMYALGIA-RHEUMATICA

Authors
SHINTANI S TSURUOKA S TAMAKI M MIHARA N SHIIGAI T KIKUCHI M
Citation
S. Shintani et al., IMMUNOFLUORESCENCE STUDY OF IMMUNE-COMPLEXES IN POLYMYALGIA-RHEUMATICA, Journal of the neurological sciences, 128(1), 1995, pp. 103-106
Citations number
8
Categorie Soggetti
Neurosciences
Journal title
Journal of the neurological sciences → ACNP
ISSN journal
0022510X
Volume
128
Issue
1
Year of publication
1995
Pages
103 - 106
Database
ISI
SICI code
0022-510X(1995)128:1<103:ISOIIP>2.0.ZU;2-M
Abstract
Two elderly patients with polymyalgia rheumatica (PMR), one with and t he other without temporal arteritis (TA), are presented. Immunofluores cence study of muscle biopsy specimens showed IgG, IgA, and fibrinogen deposits in the perifascicular area in the perimysium. This finding s uggests that immune complexes play a role in the pathogenesis of this condition and that the pathophysiology of PMR involves an interstitial inflammatory process.