EFFECTS OF BUSPIRONE ON INFLUENZA-A VIRUS-INFECTION IN STRESSED MICE

Authors
FREIREGARABAL M NUNEZ MJ LOSADA C PEREIRO D CASTROBOLANO C GANDARA J VARELAPATINO MP REYMENDEZ M
Citation
M. Freiregarabal et al., EFFECTS OF BUSPIRONE ON INFLUENZA-A VIRUS-INFECTION IN STRESSED MICE, Life sciences, 56(9), 1995, pp. 187-193
Citations number
23
Categorie Soggetti
Biology,"Medicine, Research & Experimental","Pharmacology & Pharmacy
Journal title
Life sciences → ACNP
ISSN journal
00243205
Volume
56
Issue
9
Year of publication
1995
Pages
187 - 193
Database
ISI
SICI code
0024-3205(1995)56:9<187:EOBOIV>2.0.ZU;2-B
Abstract
Experiments were conducted to evaluate the effects of chronic buspiron e (1 mg/kg/day) on the influenza A (PR-8/34) virus specific immune inj ury in CD-1 mice exposed to a chronic auditory stressor. Treatment wit h buspirone resulted in a decrease of the stress-induced increase of v irus titers and pulmonar vascular permeability as well as in a reducti on of the mortality of mice.