DETECTION OF 5-HT(3)R-A, A 5-HT(3) RECEPTOR SUBUNIT, IN SUBMUCOSAL AND MYENTERIC GANGLIA OF RAT SMALL-INTESTINE USING IN-SITU HYBRIDIZATION

Authors
JOHNSON DS HEINEMANN SF
Citation
Ds. Johnson et Sf. Heinemann, DETECTION OF 5-HT(3)R-A, A 5-HT(3) RECEPTOR SUBUNIT, IN SUBMUCOSAL AND MYENTERIC GANGLIA OF RAT SMALL-INTESTINE USING IN-SITU HYBRIDIZATION, Neuroscience letters, 184(1), 1995, pp. 67-70
Citations number
29
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
184
Issue
1
Year of publication
1995
Pages
67 - 70
Database
ISI
SICI code
0304-3940(1995)184:1<67:DO5A5R>2.0.ZU;2-Y
Abstract
Physiological and radioligand binding studies have demonstrated the ex istence of 5-HT3 receptors in the enteric nervous system. In order to determine if the cloned 5-HT3 receptor subunit, 5-HT(3)R-A, was expres sed in the enteric nervous system of rats, we have performed in situ h ybridization with P-33-labeled cRNA antisense probes on sections of ra t small intestine. Hybridization was detected. in both submucosal and myenteric ganglia of the duodenum, jejunum, and ileum.