THE IN-VITRO EFFECT OF SODIUM MERCAPTOUNDECAHYDRODODECABORATE (BOROCAPTATE) ON SULFHYDRYL-GROUPS OF DIFFERENT RAT-TISSUES

Citation
E. Buchar et al., THE IN-VITRO EFFECT OF SODIUM MERCAPTOUNDECAHYDRODODECABORATE (BOROCAPTATE) ON SULFHYDRYL-GROUPS OF DIFFERENT RAT-TISSUES, Methods and findings in experimental and clinical pharmacology, 16(9), 1994, pp. 619-622
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
03790355
Volume
16
Issue
9
Year of publication
1994
Pages
619 - 622
Database
ISI
SICI code
0379-0355(1994)16:9<619:TIEOSM>2.0.ZU;2-L
Abstract
The effect of borocaptate on structural protein sulfhydryl (SH) groups of different organs and kidney subcellular fractions was studied in v itro. It was shown that the binding capacity of borocaptate is not the same for different tissues and subcellular fractions. The highest bin ding capacity was in the liver; while kidney and brain values were sig nificantly lower. Therefore, it appears that the same concentration of borocaptate may have different effects in various organs.