A. Kikuchi et al., AGGRESSIVE B-CELL LYMPHOMA INDUCED BY EPSTEIN-BARR-VIRUS INFECTION INERYTHRODERMIC CUTANEOUS T-CELL LYMPHOMA, British journal of dermatology, 136(1), 1997, pp. 124-128
The coexistence of two cutaneous non-Hodgkin's lymphomas of different
lineage is rare. We report a patient with an indolent erythrodermic cu
taneous T-cell lymphoma followed by an aggressive B-cell lymphoma. To
our best knowledge, this is the first report describing Epstein-Barr v
irus-associated B-cell lymphoma in a patient with cutaneous T-cell lym
phoma. We suggest that the long-standing cutaneous T-cell lymphoma, as
well as the long-term chemotherapy, suppressed host immunity and caus
ed reactivation of latent Epstein-Barr virus.