Cg. Schilling et al., TETRACAINE, EPINEPHRINE (ADRENALINE), AND COCAINE (TAC) VERSUS LIDOCAINE, EPINEPHRINE, AND TETRACAINE (LET) FOR ANESTHESIA OF LACERATIONS IN CHILDREN, Annals of emergency medicine, 25(2), 1995, pp. 203-208
Study objective: To compare the duration of anesthesia experienced wit
h lidocaine, epinephrine, and tetracaine (LET) solution and that with
tetracaine, epinephrine (Adrenalin), and cocaine (TAC) solution during
suturing of uncomplicated lacerations on the face or scalp. Design: D
ouble-blind, randomized, controlled trial. Setting: The emergency depa
rtment of a university-affiliated private children's hospital. Partici
pants: One hundred seventy-one children with lacerations on the face a
nd scalp requiring suturing. Interventions: After standard application
of the anesthetic solution, patients were assessed for signs of disco
mfort before and during laceration repair. Duration of anesthesia duri
ng laceration repair was determined on the basis of the length of time
after removal of the anesthetic solution to the first sign(s) of disc
omfort that required additional anesthesia. Results: There was no stat
istical difference between TAC and LET in adequacy of anesthesia befor
e suturing or in duration of anesthesia during suturing. Conclusion: L
ET is an effective alternative to TAC for topical anesthesia during su
turing of uncomplicated lacerations on the face and scalp in children.