E. Littman et al., RATE OF INFORMATION-PROCESSING IN PATIENTS WITH WILSONS-DISEASE, The Journal of neuropsychiatry and clinical neurosciences, 7(1), 1995, pp. 68-71
This study investigated the rate of information processing, independen
t of motor speed, in neurologically affected Wilson's disease (WD) pat
ients. Two scanning tasks based on the Sternberg item-recognition para
digm were administered to 17 neurologically symptomatic WD patients an
d 17 normal control (NC) subjects. Although WD subjects do have longer
response latencies than NC subjects, their rate of information proces
sing is the same as the rate of the NC subjects. The longer response l
atencies are attributable to their motor deficits. The clear impact of
motor impairment on test performance underlines the necessity for spe
cialized assessment measures that can accurately reflect the cognitive
abilities of motor-impaired patients. These findings suggest that Wil
son's disease is not characterized by slowed information processing.