The cases of 5 patients with seizures occurring the day of or shortly
before their weddings are presented. Major life events may precipitate
or exacerbate epileptic or nonepileptic seizures as a result of 1) mi
ssed medications, 2) sleep deprivation, 3) alcohol or concomitant medi
cations, 4) hyperventilation, or 5) the emotional state directly or st
ress indirectly. Seizures occurring at times of psychological stress m
ay be either neurological or psychiatric in origin. The physician trea
ting patients with a new onset or exacerbation of seizures around a ma
jor life event must consider all of these factors in the evaluation.