Eg. Stoupel et al., RELATIONSHIP BETWEEN IMMUNOGLOBULIN LEVELS AND EXTREMES OF SOLAR-ACTIVITY, International journal of biometeorology, 38(2), 1995, pp. 89-91
The possible relationship between epidemics and extremes of solar acti
vity has been discussed previously. The purpose of the present study w
as to verify whether differences in the levels of immunoglobulins (IgA
, IgG, IgM) could be noted at the highest (July 1989) and lowest (Sept
ember 1986) points of the last (21st) and present (22nd) 11-year solar
cycle. The work was divided into a 1-month study (covering the month
of minimal or maximal solar activity), a 3-month study (1 month before
and after the month of minimal or maximal solar activity) and a 5-mon
th study (2 months before and after the month of minimal or maximal so
lar activity). A trend of a drop-off for all three immunoglobulins was
seen on the far side of the maximal point of the solar cycle. Statist
ical significance was achieved in the 5-month study for IgM (P=0.04),
and a strong trend was shown for IgG (P=0.07). Differences between the
sexes were also noted.