ASSIGNMENT OF THE 36.5-KDA (RFC5), 37-KDA (RFC4), 38-KDA (RFC3), AND 40-KDA (RFC2) SUBUNIT GENES OF HUMAN REPLICATION FACTOR-C TO CHROMOSOME BAND-12Q24.2-Q24.3, BAND-3Q27, BAND-13Q12.3-Q13, AND BAND-7Q11.23

Authors
OKUMURA K NOGAMI M TAGUCHI H DEAN FB CHEN M PAN ZQ HURWITZ J SHIRATORI A MURAKAMI Y OZAWA K EKI T
Citation
K. Okumura et al., ASSIGNMENT OF THE 36.5-KDA (RFC5), 37-KDA (RFC4), 38-KDA (RFC3), AND 40-KDA (RFC2) SUBUNIT GENES OF HUMAN REPLICATION FACTOR-C TO CHROMOSOME BAND-12Q24.2-Q24.3, BAND-3Q27, BAND-13Q12.3-Q13, AND BAND-7Q11.23, Genomics, 25(1), 1995, pp. 274-278
Citations number
14
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
25
Issue
1
Year of publication
1995
Pages
274 - 278
Database
ISI
SICI code
0888-7543(1995)25:1<274:AOT3(3>2.0.ZU;2-8
Abstract
Replication factor C is a multimeric primer-recognition protein consis ting of five subunits (p145, p40, p38, p37, and p36.5) and is essentia l for the processive elongation of DNA chains catalyzed by DNA polymer ase delta or epsilon in human cells. We have mapped the locations on h uman chromosomes of the genes coding for the four smaller subunits [p3 6.5 (RFC5), p37 (RFC4), p38 (RFC3), and p40 (RFC2)] using both PCR amp lification from DNAs of a panel of somatic hybrids and fluorescence in situ hybridization to bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q1 1.23, respectively. (C) 1995 Academic Press, Inc.