The q21 region of chromosome 17 contains the gene BRCA1, which is invo
lved in familial early-onset breast and ovarian cancers. A physical ma
p of a region that extends from a distal boundary of the BRCA1 region,
D17578, to GP2B has been constructed. The map consists of 30 STSs, in
cluding 2 new short tandem repeat polymorphic markers. The contig is c
omposed of a mixture of 7 YACs, 5 P1 plasmids, and 14 cosmids and was
ordered by STS-content mapping. (C) 1995 Academic Press, Inc.