STRUCTURE OF THE MOUSE H2A.X GENE AND PHYSICAL LINKAGE TO THE UPS LOCUS ON CHROMOSOME-9 - ASSIGNMENT OF THE HUMAN H2A.X GENE TO 11Q23 BY SEQUENCE-ANALYSIS

Authors
PORCHER C GRANDCHAMP B
Citation
C. Porcher et B. Grandchamp, STRUCTURE OF THE MOUSE H2A.X GENE AND PHYSICAL LINKAGE TO THE UPS LOCUS ON CHROMOSOME-9 - ASSIGNMENT OF THE HUMAN H2A.X GENE TO 11Q23 BY SEQUENCE-ANALYSIS, Genomics, 25(1), 1995, pp. 312-313
Citations number
7
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
25
Issue
1
Year of publication
1995
Pages
312 - 313
Database
ISI
SICI code
0888-7543(1995)25:1<312:SOTMHG>2.0.ZU;2-6
Abstract
The H2A.X gene was cloned from the C3H mouse strain, and its structure was determined, Sequence analysis revealed that this gene is situated in close proximity to the porphobilinogen deaminase (PBGD) gene in th e opposite orientation. The synteny is conserved in human, This permit s us to assign the H2A.X gene to chromosome 9 and 11q23 in mouse and h uman, respectively. (C) 1995 Academic Press, Inc.