SYNTHETIC STUDIES TOWARDS MILBEMYCIN BETA(3) - RAPID CONSTRUCTION OF A MODEL SPIROKETAL SUBUNIT USING THE INTRAMOLECULAR SILYL MODIFIED SAKURAI (ISMS) METHODOLOGY

Authors
MARKO IE BAILEY M MURPHY F DECLERCQ JP TINANT B FENEAUDUPONT J KRIEF A DUMONT W
Citation
Ie. Marko et al., SYNTHETIC STUDIES TOWARDS MILBEMYCIN BETA(3) - RAPID CONSTRUCTION OF A MODEL SPIROKETAL SUBUNIT USING THE INTRAMOLECULAR SILYL MODIFIED SAKURAI (ISMS) METHODOLOGY, Synlett, (1), 1995, pp. 123-126
Citations number
38
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
1
Year of publication
1995
Pages
123 - 126
Database
ISI
SICI code
0936-5214(1995):1<123:SSTMB->2.0.ZU;2-B
Abstract
The ISMS condensation between allyl silane 3 and ortholactone 13 smoot hly leads, after oxidative cleavage and stereoselective reduction, to spiroketal 2b, a model for the subunit present in milbemycin beta(3).