THE SYNTHESIS, AND DOPAMINE D-2 AND SEROTONIN 5-HT3 RECEPTOR AFFINITYOF 3-AZA ANALOGS (PYRIDYL) OF 4-AMINO-5-CHLORO-2-METHOXYBENZAMIDES

Authors
COLDWELL MC GADRE A JERMAN J KING FD NASH D
Citation
Mc. Coldwell et al., THE SYNTHESIS, AND DOPAMINE D-2 AND SEROTONIN 5-HT3 RECEPTOR AFFINITYOF 3-AZA ANALOGS (PYRIDYL) OF 4-AMINO-5-CHLORO-2-METHOXYBENZAMIDES, Bioorganic & medicinal chemistry letters, 5(1), 1995, pp. 39-42
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
1
Year of publication
1995
Pages
39 - 42
Database
ISI
SICI code
0960-894X(1995)5:1<39:TSADDA>2.0.ZU;2-R
Abstract
The synthesis of potential metabolically blocked 3-aza analogues (pyri dyl) of 4-amino-5-chloro-2-methoxybenzamides is described. Retention o f dopamine D-2 and serotonin 5-HT3 receptor affinity is observed.