Neonatal and follow-up data of infants from the special care nursery w
hose birth weights were < 750 g, born between 1980 and 1990, were revi
ewed. There was a 20% relative improvement in the odds of surviving th
e neonatal period, a 16% improvement in the odds of being discharged a
nd a 19% improvement in the odds of surviving until 2 years of age wit
h each consecutive year. Home oxygen use increased significantly over
the study period. The neurodevelopmental outcomes of infants were simi
lar over the 11-year period, with 53% being classified as neurological
ly normal, with a mean developmental index of 83 at 1 to 2 years of ag
e. We conclude that there has been an improved survival of infants wit
h birth weights <750g in our institution, and that the overall inciden
ce of serious neurodevelopmental deficits among survivors has remained
stable.