Antiphospholipid syndrome is a paradoxical disease state with in vitro
prolongation of activated partial thromboplastin time and a strong pr
edilection for in vivo thrombosis. The syndrome can be associated with
systemic lupus erythematosus or lupus-like diseases or may be primary
, presenting with thrombotic phenomena in young patients with no risk
factors for thrombosis. We present two cases seen in two different set
tings in the hospital.