Exposures of as little as 2.5 per cent of the body surface to concentr
ated hydrofluoric acid (HF) may be fatal. Survival after major HF expo
sures is facilitated by aggressive emergency management which, we feel
, includes wound irrigation, subeschar injection of calcium gluconate,
monitored supplementation of serum calcium, and prompt wound excision
carried out as an emergency procedure. The following case reports and
literature review illustrate the important differences between exposu
res to concentrated HF of as little as 2 per cent of the body surface
and smaller exposures to concentrated HF or exposure to dilute HF.