A CASE OF PRIMARY HODGKINS-DISEASE OF THE STOMACH

A case of primary Hodgkin's disease, a lymphocyte-predominant entity, occurring in the stomach is described. The patient was a 37-year-old m an who complained of general fatigue. Endoscopic biopsy revealed gastr ic malignant lymphoma. Subtotal gastrectomy and postoperative chemothe rapy following a modified CHOP regimen were performed. The patient has been free of recurrence during a follow-up period of 15 months. The p reoperative diagnosis of gastric Hodgkin's disease is difficult. Thus far, of 100 cases of gastric Hodgkin's disease reported in Japan, only 3 were diagnosed correctly preoperatively. We also misdiagnosed our c ase, as B cell type malignant lymphoma, preoperatively. The final diag nosis of Hodgkin's disease of the stomach was made on the basis of his topathological and immunohistochemical examinations. Hodgkin's disease of the stomach is rare, and there are histologically similar diseases ; Ki-1 lymphoma, adult T cell lymphoma, malignant histiocytosis, and i nfectious monocytosis. Careful diagnosis is essential thus for Hodgkin 's disease of the stomach.