We studied the physiologic and clinical responses to moderate altitude
in 97 older men and women (aged 59 to 83 years) over 5 days in Vail,
Colorado, at an elevation of 2,500 m (8,200 ft). The incidence of acut
e mountain sickness was 16%, which is slightly lower than that reporte
d for younger persons. The occurrence of symptoms of acute mountain si
ckness did not parallel arterial oxygen saturation or spirometric or b
lood pressure measurements. Chronic diseases were present in percentag
es typical for ambulatory elderly persons: 19 (20%) had coronary arter
y disease, 33 (34%) had hypertension, and 9 (9%) had lung disease. Des
pite this, no adverse signs or symptoms occurred in our subjects durin
g their stay at this altitude. Our findings suggest that persons with
preexisting, generally asymptomatic, cardiovascular or pulmonary disea
se can safely visit moderate altitudes.