GRANULOCYTE-COLONY-STIMULATING FACTOR TREATMENT FOR NEONATAL NEUTROPENIA

Authors
RUSSELL ARB DAVIES EG BALL SE GORDONSMITH E
Citation
Arb. Russell et al., GRANULOCYTE-COLONY-STIMULATING FACTOR TREATMENT FOR NEONATAL NEUTROPENIA, Archives of Disease in Childhood, 72(1), 1995, pp. 53-54
Citations number
6
Categorie Soggetti
Pediatrics
Journal title
Archives of Disease in Childhood → ACNP
ISSN journal
00039888
Volume
72
Issue
1
Year of publication
1995
Pages
53 - 54
Database
ISI
SICI code
0003-9888(1995)72:1<53:GFTFNN>2.0.ZU;2-N
Abstract
In a pilot study recombinant granulocyte colony-stimulating (rhG-CSF) was administered to 12 neutropenic preterm infants do determine if neo natal neutropenia is secondary to decreased endogenous G-CSF productio n, Respiratory variables were monitored because of the possible link b etween inflammatory cells and hyaline membrane disease. All infants sh owed increased neutrophil counts. The only possible side effect observ ed was an exacerbation of thrombocytopenia.